The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2009

Filed:

Nov. 26, 2004
Applicants:

Shey-shing Sheu, Pittsford, NY (US);

Marion W. Anders, Pittsford, NY (US);

Lin Xu, Lexington, MA (US);

Virendra K. Sharma, Pittsford, NY (US);

Inventors:

Shey-Shing Sheu, Pittsford, NY (US);

Marion W. Anders, Pittsford, NY (US);

Lin Xu, Lexington, MA (US);

Virendra K. Sharma, Pittsford, NY (US);

Assignee:

University of Rochester, Rochester, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 37/00 (2006.01); A61K 31/24 (2006.01); C07C 229/00 (2006.01); C07C 205/00 (2006.01); C07C 261/00 (2006.01); C07C 269/00 (2006.01); C07C 271/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are hydrophilic choline/N-heterocycle ester compounds containing single amino acids, peptides, or derivatives thereof which have the potential to express anti-oxidant activity capable of reducing reactive oxygen species in cells. These compounds may be used to inhibit oxidative stress-induced cell injury or death both in vivo and ex vivo. In addition, methods for the synthesis of these compounds are disclosed.


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