The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2009
Filed:
Feb. 14, 2002
Paul A. Wender, Menlo Park, CA (US);
Jonathan B. Rothbard, Cupertino, CA (US);
Lee Wright, Redwood City, CA (US);
Erik L. Kreider, Sunnyvale, CA (US);
Christopher L. Vandeusen, Columbus, CA (US);
Paul A. Wender, Menlo Park, CA (US);
Jonathan B. Rothbard, Cupertino, CA (US);
Lee Wright, Redwood City, CA (US);
Erik L. Kreider, Sunnyvale, CA (US);
Christopher L. VanDeusen, Columbus, CA (US);
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Cellgate, Inc., Sunnyvale, CA (US);
Abstract
The present invention provides compositions and methods for enhancing transport of biologically active compounds across biological membranes and across and into animal epithelial or endothelial tissues. The composition includes a biologically active agent and a transport moiety. The transport moiety includes a structure selected from the group consisting of (ZYZ)Z, (ZY)Z, (ZYY)Z and (ZYYY)Z. Subunit 'Z' is L-arginine or D-arginine, and subunit 'Y' is an amino acid that does not comprise an amidino or guanidino moiety. Subscript “n” is an integer ranging from 2 to 10. The method for enhancing transport involves the administration of the aforementioned composition.