The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2009

Filed:

Sep. 17, 2004
Applicants:

Mark Hirsh, Wellesley, MA (US);

Jane Hirsh, Wellesley, MA (US);

Whe-yong Lo, Canton, MA (US);

Inventors:

Mark Hirsh, Wellesley, MA (US);

Jane Hirsh, Wellesley, MA (US);

Whe-Yong Lo, Canton, MA (US);

Assignee:

Collegium Pharmaceutical, Inc., Cumberland, RI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/24 (2006.01); A61K 9/20 (2006.01); A61K 9/22 (2006.01); A61K 9/28 (2006.01); A61K 9/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compositions containing both a sedative compound and a non-sedative antihistamine are provided. More particularly, compositions for administration at bedtime containing a sedating antihistamine or other sedating compound in immediate release form and a non-sedating antihistamine in delayed-release form are described. Alternatively, a composition, for administrating upon awakening, containing a non-sedating antihistamine in immediate release form, and a sedating antihistamine or other sedative in delayed-release form is described. Methods of inhibiting the release of histamines by administration of the compositions to a mammalian subject are also provided. The dosage forms may comprise other medications, such as leukotriene receptor antagonists, to enhance the suppression of histamine symptoms.


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