The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2009
Filed:
Nov. 16, 2005
Ian Foltz, Burnaby, CA;
Raffaella Faggioni, Pleasanton, CA (US);
Giorgio Senaldi, Dublin, CA (US);
Kathy Manchulenko, Port Coquitlam, CA;
Jaspal S. Kang, British Columbia, CA;
Palaniswami Rathanaswami, Vancouver, CA;
Kiran Ahluwalia, Fremont, CA (US);
Orit Foord, Foster City, CA (US);
Scott Klakamp, Fremont, CA (US);
Ian Foltz, Burnaby, CA;
Raffaella Faggioni, Pleasanton, CA (US);
Giorgio Senaldi, Dublin, CA (US);
Kathy Manchulenko, Port Coquitlam, CA;
Jaspal S. Kang, British Columbia, CA;
Palaniswami Rathanaswami, Vancouver, CA;
Kiran Ahluwalia, Fremont, CA (US);
Orit Foord, Foster City, CA (US);
Scott Klakamp, Fremont, CA (US);
Amgen Inc., Thousand Oaks, CA (US);
Abstract
The present invention is related to antibodies directed to IL-13 and uses of such antibodies. For example, in accordance with the present invention, there are provided human monoclonal antibodies directed to IL-13. Isolated polynucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions (FR's) and/or complementarity determining regions (CDR's), are provided. Additionally, methods of using these antibodies to treat patients are also provided. Additionally, IL-13 dependent biomarkers and methods of their identification and use are also provided.