The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 01, 2009

Filed:

Jun. 07, 2004
Applicants:

Youla S. Tsantrizos, Montreal, CA;

Anne-marie Faucher, St-Placide, CA;

Jean Rancourt, Laval, CA;

Peter White, Montreal, CA;

Inventors:

Youla S. Tsantrizos, Montreal, CA;

Anne-Marie Faucher, St-Placide, CA;

Jean Rancourt, Laval, CA;

Peter White, Montreal, CA;

Assignee:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/445 (2006.01); C07D 211/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

The use of a compound of formula (II): or its enantiomers or diastereoisomers thereof, or salts or pharmaceutically-acceptable esters thereof, in the treatment or prevention of a papilloma virus infection, particularly human papilloma virus in a mammal, wherein R; X; X; X; R; R; W; Z; Y; T; and Rare defined herein. The present invention also provides novel compounds, pharmaceutical compositions and methods for using these compounds and compositions in the treatment or prevention of papilloma virus infection. More particularly, the present invention provides compounds, compositions and methods for inhibiting papilloma virus DNA replication by interfering with the E1-E2 protein-protein interaction essential for viral DNA replication.


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