The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7582738 B1

PDF
Full Text
Expired
Date of Patent:
Sep. 01, 2009

Filed:

Dec. 06, 2005
Applicants:

Kejian Zhang, Cincinnati, OH (US);

Richard J. Wenstrup, Cincinnati, OH (US);

Alexandra H. Filipovich, Covington, KY (US);

Inventors:

Kejian Zhang, Cincinnati, OH (US);

Richard J. Wenstrup, Cincinnati, OH (US);

Alexandra H. Filipovich, Covington, KY (US);

Assignee:

Children's Hospital Medical Center, Cincinnati, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/00 (2006.01); C12Q 1/68 (2006.01); C12P 19/34 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The methods and compositions of the invention find use in the clinical diagnosis of primary immunodeficiencies, particularly Wiskott-Aldrich related syndromes. The compositions of the invention include isolated nucleic acid molecules and oligonucleotide pairs suitable for use in amplifying regions of the Wiskott-Aldrich syndrome protein gene and in determining the nucleotide sequence of the Wiskott-Aldrich syndrome protein gene in a patient. The invention facilitates efficient, cost-effective amplification of one or more regions of the Wiskott-Aldrich syndrome protein gene. The nucleotide sequence of amplified DNA comprising one or more regions of the Wiskott-Aldrich Syndrome Protein gene can be determined using the methods and compositions of the invention. Knowledge of the patient's nucleotide sequence in the Wiskott-Aldrich Syndrome Protein gene allows diagnosis of the patient's primary immunodeficiency.


Find Patent Forward Citations

Zhang, Kejian. (2009). Diagnostic assay for wiskott-aldrich syndrome and genetically related disorders (U.S. Patent No. 7582738). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7582738

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