The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 01, 2009

Filed:

Jul. 20, 2005
Applicants:

Shang-cheng Hung, Taipei, TW;

Jing-chyi Lee, Houbi Township, Tainan County, TW;

Xin-an LU, Tongluo Township, Miaoli County, TW;

Inventors:

Shang-Cheng Hung, Taipei, TW;

Jing-Chyi Lee, Houbi Township, Tainan County, TW;

Xin-An Lu, Tongluo Township, Miaoli County, TW;

Assignee:

Academia Sinica, Taipei, TW;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C08B 37/10 (2006.01); C13K 5/00 (2006.01); C13K 7/00 (2006.01); C07H 5/04 (2006.01); C07H 5/06 (2006.01); C08B 37/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Orthogonally protected disaccharide building blocks for synthesis of heparin oligosaccharide. The disaccharide building block has a formula (I), in which L is a leaving group, P, P, Pand are different, and of them Pis an ester-type protecting group, Pis a hydroxyl protecting group that could be oxidized to a carboxylic acid, Pis a hydroxyl protecting group, and Pis a hydroxyl protecting group which allows chemoslective deprotection with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ). Acting as an elongation unit, the disaccharide building block of formula (I) may react with a starting unit of formula (II) to synthesize a heparin oligosaccharide.


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