The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 01, 2009
Filed:
Jan. 25, 2008
Yves Leblanc, Kirkland, CA;
David Powell, Verdun, CA;
Yeeman K. Ramtohul, Pierrefonds, CA;
Serge Léger, Notre-Dame-de-l'ile-Perrot, CA;
Yves Leblanc, Kirkland, CA;
David Powell, Verdun, CA;
Yeeman K. Ramtohul, Pierrefonds, CA;
Serge Léger, Notre-Dame-de-l'ile-Perrot, CA;
Merck Frosst Canada L.L.C., Kirkland, Quebec, CA;
Abstract
Azacycloalkane derivatives of structural formula I are selective inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis; obesity; diabetes; neurological disease; metabolic syndrome; insulin resistance; and liver steatosis.