The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 01, 2009
Filed:
Mar. 07, 2007
Benjamin Neuman, Brightwell-Cum-Sotwell, GB;
David A. Stein, Corvallis, OR (US);
Michael Buchmeier, Encinitas, CA (US);
Patrick L. Iversen, Corvallis, OR (US);
Benjamin Neuman, Brightwell-Cum-Sotwell, GB;
David A. Stein, Corvallis, OR (US);
Michael Buchmeier, Encinitas, CA (US);
Patrick L. Iversen, Corvallis, OR (US);
AVI Biopharma, Inc., Corvallis, OR (US);
The United States of America as represented by the Department of Health and Human Services, Washington, DC (US);
Abstract
The invention provides antisense antiviral compounds and methods of their use and production in inhibition of growth of viruses of the Arenaviridae family and in the treatment of a viral infection. The compounds are particularly useful in the treatment of Arenavirus infection in a mammal. The antisense antiviral compounds are substantially uncharged morpholino oligonucleotides have a sequence of 12-40 subunits, including at least 12 subunits having a targeting sequence that is complementary to a region associated with viral RNA sequences within a 19 nucleotide region of the 5'-terminal regions of the viral RNA, viral complementary RNA and/or mRNA identified by SEQ ID NO:1.