The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 01, 2009
Filed:
Apr. 18, 2007
Jeff G. Hall, Madison, WI (US);
Zbigniev Skrzypczynski, Verona, WI (US);
Sarah Wayland, Madison, WI (US);
Ned D. Reimer, Madison, WI (US);
Luis P. Reynaldo, Madison, WI (US);
Joerg Baier, Verona, WI (US);
Victor Lyamichev, Madison, WI (US);
Bruce P. Neri, Madison, WI (US);
Jeff G. Hall, Madison, WI (US);
Zbigniev Skrzypczynski, Verona, WI (US);
Sarah Wayland, Madison, WI (US);
Ned D. Reimer, Madison, WI (US);
Luis P. Reynaldo, Madison, WI (US);
Joerg Baier, Verona, WI (US);
Victor Lyamichev, Madison, WI (US);
Bruce P. Neri, Madison, WI (US);
Third Wave Technologies, Inc., Madison, WI (US);
Abstract
The present invention provides compositions comprising oligonucleotides that have 3' end groups (e.g. lipophilic moieties) that are useful in invasive cleavage reactions such as the INVADER assay. Specifically, the present invention provides compositions containing oligonucleotides with 3′ end groups configured for generating a detectable signal in invasive cleavages assays with a high signal-to-background ratio, as well as methods for generating such compositions.