The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2009
Filed:
Oct. 17, 2002
Stephen Maxwell Taylor, Bellbird Park, AU;
Ian Alexander Shiels, Muirlea, AU;
David Fairlie, Springwood, AU;
Darren March, Banks, AU;
Michael Whitehouse, Holland Park W., AU;
Stephen Maxwell Taylor, Bellbird Park, AU;
Ian Alexander Shiels, Muirlea, AU;
David Fairlie, Springwood, AU;
Darren March, Banks, AU;
Michael Whitehouse, Holland Park W., AU;
Promics Pty Limited, Macquarie Park, New South Wales, AU;
Abstract
The invention relates to novel cyclic compounds which have the ability to modulate the activity of G protein-coupled receptors. The compounds preferably act as antagonists. In preferred embodiments, the invention provides cyclic peptidic and peptidomimetic antagonists of C5a receptors, which are active against C5a receptors on polymorphonuclear leukocytes and macrophages. The compounds of the invention are both potent and selective, and are useful in the treatment of a variety of inflammatory conditions.