The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2009
Filed:
Mar. 13, 2006
Applicants:
Nader Fotouhi, Basking Ridge, NJ (US);
Gregory Jay Haley, San Diego, CA (US);
Klaus B. Simonsen, Frederiksberg, DK;
Binh Thanh VU, North Caldwell, NJ (US);
Stephen Evan Webber, San Diego, CA (US);
Inventors:
Nader Fotouhi, Basking Ridge, NJ (US);
Gregory Jay Haley, San Diego, CA (US);
Klaus B. Simonsen, Frederiksberg, DK;
Binh Thanh Vu, North Caldwell, NJ (US);
Stephen Evan Webber, San Diego, CA (US);
Assignee:
Hoffman-La Roche Inc., Nutley, NJ (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4164 (2006.01); C07D 233/08 (2006.01);
U.S. Cl.
CPC ...
Abstract
There are presented compounds of the formula or pharmaceutically acceptable salts thereof,wherein Y, Y, X, X, Xand R are as described in this application. These compounds are believed to inhibit MDM2-p53 interaction and as such the compounds will have anti-hyperproliferative cellular activity.