The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 25, 2009

Filed:

Dec. 04, 2002
Applicants:

Bernd Nickel, Mühltal, DE;

Istvan Szelenyi, Schwaig, DE;

Jürgen Schmidt, Uhldingen Mühlhofen, DE;

Peter Emig, Bruchköbel, DE;

Dietmar Reichert, Eschau, DE;

Eckhard Günther, Maintal, DE;

Kay Brune, Marloffstein, DE;

Guillaume Le Baut, Saint Sebastian/Loire, DE;

Inventors:

Bernd Nickel, Mühltal, DE;

Istvan Szelenyi, Schwaig, DE;

Jürgen Schmidt, Uhldingen Mühlhofen, DE;

Peter Emig, Bruchköbel, DE;

Dietmar Reichert, Eschau, DE;

Eckhard Günther, Maintal, DE;

Kay Brune, Marloffstein, DE;

Guillaume Le Baut, Saint Sebastian/Loire, DE;

Assignee:

ZIOPHRAM Oncology, Inc., Charlestown, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); C07D 401/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to the use of N-substituted indole-3-glyoxylamides of the general formula I as antitumor agents and to a pharmaceutical composition having antitumor action, characterized in that it contains at least one of the compounds of the general formula 1, if appropriate also in the form of the physiologically tolerable acid addition salts or N-oxides. Furthermore, the invention also includes antitumor agents comprising as active compound one or more N-substituted indole-3-glyoxylamides according to the general formula 1 and, if appropriate, their physiologically tolerable acid addition salts and, if possible, N-oxides and a pharmaceutically utilizable carrier and/or diluent or auxiliary substance in the form of tablets, coated tablets, capsules, solutions for infusion or ampoules, suppositories, patches, powder preparations which can be employed by inhalation, suspensions, creams and ointments.


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