The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 25, 2009

Filed:

Jan. 05, 2006
Applicants:

Winston J. Thomas, San Mateo, CA (US);

Dennis T. Drayna, Bethesda, MD (US);

John N. Feder, Mountain View, CA (US);

Andreas Gnirke, San Carlos, CA (US);

David Ruddy, San Francisco, CA (US);

Zenta Tsuchihashi, Menlo Park, CA (US);

Roger K. Wolff, Mill Valley, CA (US);

Inventors:

Winston J. Thomas, San Mateo, CA (US);

Dennis T. Drayna, Bethesda, MD (US);

John N. Feder, Mountain View, CA (US);

Andreas Gnirke, San Carlos, CA (US);

David Ruddy, San Francisco, CA (US);

Zenta Tsuchihashi, Menlo Park, CA (US);

Roger K. Wolff, Mill Valley, CA (US);

Assignee:

Bio-Rad Laboratories, Inc., Hercules, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C12N 15/00 (2006.01); C12P 21/00 (2006.01); C12N 15/70 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates generally to the gene, and mutations thereto, that are responsible for the disease hereditary hemochromatosis (HH). More particularly, the invention relates to the identification, isolation, and cloning of the DNA sequence corresponding to the normal and mutant HH genes, as well as the characterization of their transcripts and gene products. The invention also related to methods and the like for screening for HH homozygotes and further relates to HH diagnosis, prenatal screening and diagnosis, and therapies of HH disease, including gene therapeutics, protein and antibody based therapeutics, and small molecule therapeutics.


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