The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 25, 2009

Filed:

Nov. 28, 2005
Applicants:

Sharon JO Keeler, Bear, DE (US);

Sheryl M. Wolstenholme, Elkton, MD (US);

Jodie L. Duke, Newark, DE (US);

Linda L. Hnatow, Oxford, PA (US);

Inventors:

Sharon Jo Keeler, Bear, DE (US);

Sheryl M. Wolstenholme, Elkton, MD (US);

Jodie L. Duke, Newark, DE (US);

Linda L. Hnatow, Oxford, PA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/38 (2006.01); A61K 39/085 (2006.01);
U.S. Cl.
CPC ...
Abstract

A process was developed for expressing antimicrobial peptides in a recombinant host cell that eliminates host cell toxicity and antimicrobial peptide degradation, as well as providing a process for rapid purification. Fusion proteins comprising a periplasmic targeting signal, cleavage site, and antimicrobial peptides provide the basis for this process which produces antimicrobial peptides that may be used in antimicrobial compositions and articles.


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