The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 18, 2009
Filed:
May. 02, 2005
Applicants:
Wolfgang Glaesner, Indianapolis, IN (US);
Rohn Lee Millican, Jr., Indianapolis, IN (US);
Yu Tian, Carmel, IN (US);
Sheng-hung Rainbow Tschang, Carmel, IN (US);
Inventors:
Wolfgang Glaesner, Indianapolis, IN (US);
Rohn Lee Millican, Jr., Indianapolis, IN (US);
Yu Tian, Carmel, IN (US);
Sheng-Hung Rainbow Tschang, Carmel, IN (US);
Assignee:
Eli Lilly and Company, Indianapolis, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 14/435 (2006.01); C07K 14/50 (2006.01); C07K 14/76 (2006.01); C12P 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention provides specific FGF-21 compounds fused to specific IgG4-Fc or HSA derivatives resulting in fusion proteins that are biologically active with an extended elimination half-life and a slower clearance. These FGF-21 compound fusion proteins and compositions are useful in treating type 2 diabetes, obesity, and metabolic syndrome.