The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 18, 2009
Filed:
Apr. 08, 2004
Mary Jane Cardosa, Penang, MY;
Hamid Sharifah, Penang, MY;
Shirley Samuel-verghese, Kuala Lumpur, MY;
Elumalai Sunderasan, Kuala Lumpur, MY;
Hoong Yeet Yeang, Kuala Lumpur, MY;
Hamzah Samsidar, Kuala Lumpur, MY;
Mary Jane Cardosa, Penang, MY;
Hamid Sharifah, Penang, MY;
Shirley Samuel-Verghese, Kuala Lumpur, MY;
Elumalai Sunderasan, Kuala Lumpur, MY;
Hoong Yeet Yeang, Kuala Lumpur, MY;
Hamzah Samsidar, Kuala Lumpur, MY;
The Board of the Rubber Research Institute of Malaysia, Kuata Lumpur, MY;
Universiti Sains Malaysia, Kuala Lumpur, ML;
Abstract
This invention relates to allergenic proteins of natural rubber latex in substantially purified form, their production and their use, together with monoclonal antibodies developed against those allergenic proteins, in assays for the qualitative and quantitative determination of the levels of the allergenic proteins in natural rubber latex or in products made from latex. Assays for identifying and/or quantitating antibodies in blood or blood products that mediate the occurrence of an allergic reaction induced by natural rubber latex are also provided, together with in vivo and in vitro diagnostic tests for detecting hypersensitivity to natural rubber latex and which involve use of the aforesaid allergenic proteins. The invention also provides for the use of the aforesaid allergens as de-sensitising agents in the treatment of latex protein allergy. There is still further provided a method for removing allergenic proteins from latex products.