The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 18, 2009
Filed:
Jan. 26, 2004
Stephen J. Karlik, Ontario, CA;
Michael A. Pleiss, Sunnyvale, CA (US);
Andrei W. Konradi, Burlingame, CA (US);
Francine S. Farouz, Mercer Island, WA (US);
Christopher M. Semko, Fremont, CA (US);
Darren B. Dressen, San Mateo, CA (US);
Elizabeth Messersmith, El Cerrito, CA (US);
Stephen Freedman, Walnut Creek, CA (US);
Ted Yednock, Forest Knolls, CA (US);
Stephen J. Karlik, Ontario, CA;
Michael A. Pleiss, Sunnyvale, CA (US);
Andrei W. Konradi, Burlingame, CA (US);
Francine S. Farouz, Mercer Island, WA (US);
Christopher M. Semko, Fremont, CA (US);
Darren B. Dressen, San Mateo, CA (US);
Elizabeth Messersmith, El Cerrito, CA (US);
Stephen Freedman, Walnut Creek, CA (US);
Ted Yednock, Forest Knolls, CA (US);
Elan Pharmaceuticals, Inc., South San Francisco, CA (US);
Abstract
The application provides for methods and compositions for inhibiting demyelination, promoting remyelination and/or treating paralysis in a subject in need thereof. Preferably, such compositions include immunoglobulins (e.g., antibodies, antibody fragments, and recombinantly produced antibodies or fragments), polypeptides (e.g., soluble forms of the ligand proteins for integrins) and small molecules, which when administered in an effective amount inhibits demyelination and/or promotes remyelination in a patient. The compositions and methods described herein can also utilize other anti-inflammatory agents used to palliate conditions and diseases associated with demyelination.