The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 18, 2009
Filed:
Jan. 12, 2007
Applicants:
Stanley Belkowski, Norristown, PA (US);
Michael R. D'andrea, Cherry Hill, NJ (US);
Inventors:
Stanley Belkowski, Norristown, PA (US);
Michael R. D'Andrea, Cherry Hill, NJ (US);
Assignee:
Ortho-McNeil Pharmaceutical, Inc., Raritan, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/37 (2006.01);
U.S. Cl.
CPC ...
Abstract
It is now discovered that human chymase cleaves human SLPI at a specific site and that this cleavage can be used as an indicator of chymase activity. The present invention provides methods of diagnosing a chymase-associated disease or evaluating the efficiency of a treatment of a chymase-associated disease in a human subject by measuring SLPI processing, as well as other related methods and compositions.