The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2009
Filed:
May. 18, 2007
Applicants:
Daniel Dix, LaGrangeville, NY (US);
Katherine Bowers, Clayton, NC (US);
Chimanlall Goolcharran, Hopewell Junction, NY (US);
Leu-fen H. Lin, White Plains, NY (US);
Inventors:
Daniel Dix, LaGrangeville, NY (US);
Katherine Bowers, Clayton, NC (US);
Chimanlall Goolcharran, Hopewell Junction, NY (US);
Leu-Fen H. Lin, White Plains, NY (US);
Assignee:
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 36/20 (2006.01); A61K 47/48 (2006.01); C07K 14/475 (2006.01);
U.S. Cl.
CPC ...
Abstract
Formulations of an interleukin-1 (IL-1) antagonist are provided including a pre-lyophilized formulation, a reconstituted lyophilized formulation, and a stable liquid formulation. Preferably, the IL-1 antagonist is an IL-1 trap composed of a dimer of two fusion protein having an amino acid sequence selected from the group consisting of SEQ ID NO: 10.