The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2009
Filed:
May. 11, 2007
Aurelia Conte, Basel, CH;
Henrietta Dehmlow, Grenzach-Wyhlen, DE;
Uwe Grether, Efringen-Kirchen, DE;
Nicole A. Kratochwil, Sool, CH;
Holger Kuehne, Grenzach-Wyhlen, DE;
Robert Narquizian, St. Louis, FR;
Constantinos Panousis, Bottmingen, CH;
Jens-uwe Peters, Grenzach-Wyhlen, DE;
Fabienne Ricklin, Hombourg, FR;
Stephan Roever, Inzlingen, DE;
Aurelia Conte, Basel, CH;
Henrietta Dehmlow, Grenzach-Wyhlen, DE;
Uwe Grether, Efringen-Kirchen, DE;
Nicole A. Kratochwil, Sool, CH;
Holger Kuehne, Grenzach-Wyhlen, DE;
Robert Narquizian, St. Louis, FR;
Constantinos Panousis, Bottmingen, CH;
Jens-Uwe Peters, Grenzach-Wyhlen, DE;
Fabienne Ricklin, Hombourg, FR;
Stephan Roever, Inzlingen, DE;
Hoffmann-La Roche Inc., Nutley, NJ (US);
Abstract
The invention is concerned with novel pyridopyrimidinone derivatives of formula (I): wherein Rto R, X, Y, m and n are as defined in the description and in the claims. The compounds of the present invention are HM74A agonists with improved properties compared to niacin and can be used for the treatment and/or prevention of diseases such as dyslipidemia, atherosclerosis, diabetes, metabolic syndrome, and other related diseases associated with HM74A.