The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2009
Filed:
Apr. 11, 2003
Oliver Schadt, Rodenbach, DE;
Henning Böttcher, Darmstadt, DE;
Joachim Leibrock, Pfungstadt, DE;
Kai Schiemann, Seeheim-Jugenheim, DE;
Timo Heinrich, Groβ-Umstadt, DE;
Günter Hölzemann, Seeheim-Jugenheim, DE;
Christoph Van Amsterdam, Darmstadt, DE;
Gerd Bartoszyk, Weiterstadt, DE;
Christoph Seyfried, Seeheim-Jugenheim, DE;
Oliver Schadt, Rodenbach, DE;
Henning Böttcher, Darmstadt, DE;
Joachim Leibrock, Pfungstadt, DE;
Kai Schiemann, Seeheim-Jugenheim, DE;
Timo Heinrich, Groβ-Umstadt, DE;
Günter Hölzemann, Seeheim-Jugenheim, DE;
Christoph van Amsterdam, Darmstadt, DE;
Gerd Bartoszyk, Weiterstadt, DE;
Christoph Seyfried, Seeheim-Jugenheim, DE;
Merck Patent GmbH, Darmstadt, DE;
Abstract
Substituted indoles of the formula (I) and physiologically acceptable derivatives and salts thereof, in which R, D, E, R, p, X, E, G, Xand Z are as defined in claim 1, exhibit particular actions on the central nervous system, especially 5HT reuptake-inhibiting and 5 HTx-agonistic and/or -antagonistic actions and in particular serotonin-agonistic and -antagonistic properties and can be employed as antipsychotics, neuroleptics, antidepressants, anxiolytics and/or antihypertonics. They can furthermore be employed as excitatory amino acid antagonists for combating neurodegenerative diseases, including cerebrovascular diseases, epilepsy, schizophrenia, Alzheimer's disease, Parkinson's disease, Huntington's disease, cerebral ischaemia, infarction or psychoses.