The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 11, 2009

Filed:

Aug. 04, 2005
Applicants:

Robert D. Berahovich, Berkeley, CA (US);

Zhenhua Miao, San Jose, CA (US);

Brett Premack, San Francisco, CA (US);

Thomas J. Schall, Palo Alto, CA (US);

Inventors:

Robert D. Berahovich, Berkeley, CA (US);

Zhenhua Miao, San Jose, CA (US);

Brett Premack, San Francisco, CA (US);

Thomas J. Schall, Palo Alto, CA (US);

Assignee:

Chemocentryx, Inc., Mt. View, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/00 (2006.01); C12Q 1/37 (2006.01);
U.S. Cl.
CPC ...
Abstract

Truncated chemokines lacking an N-terminal region that activate CCR1 and/or FPRL1 and compositions containing the truncated chemokines are provided. Methods of identifying agents that modulate CCR1 and/or FPRL1 activity either by modulating the production of the truncated chemokines or the ability of the truncated chemokines to activate CCR1 and/or FPRL1 are also disclosed. Methods using the truncated chemokines to inhibit or activate CCR1 and/or FPRL1 mediated biological activities are also disclosed.


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