The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2009
Filed:
Apr. 24, 2003
Takaomi Saido, Saitama, JP;
Nobuhisa Iwata, Saitama, JP;
Satoshi Tsubuki, Saitama, JP;
Yoshie Takaki, Saitama, JP;
Takashi Saito, Saitama, JP;
Tadashi Nakaya, Hokkaido, JP;
Takaomi Saido, Saitama, JP;
Nobuhisa Iwata, Saitama, JP;
Satoshi Tsubuki, Saitama, JP;
Yoshie Takaki, Saitama, JP;
Takashi Saito, Saitama, JP;
Tadashi Nakaya, Hokkaido, JP;
Riken, Saitama, JP;
Takeda Pharmaceutical Company, Ltd, Osaka, JP;
Abstract
The present invention provides a method of measuring the activity of neprilysin, etc. More specifically, the present invention provides a method of measuring the activity of neprilysin in nerve cells; a method of screening a protein, a peptide or a compound enhancing the activity or expression of neprilysin nerve cells by measuring the activity of neprilysin; a method of enhancing the activity or expression of neprilysin; and so on. Thus, the compound enhancing the activity and/or expression of neprilysin, which is obtained by the screening method characterized by using the method of measuring the activity of neprilysin in accordance with the present invention, is useful as a preventive and/or therapeutic agent for Alzheimer's disease. The method of measuring the activity of the present invention can be used for presymptoms diagnosis of Alzheimer's disease.