The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2009
Filed:
May. 19, 2005
Gregor Meyers, Walddorfhaeslach, DE;
Andreas Ege, Teubingen, DE;
Christiane Fetzer, Meunster, DE;
Martina Von Freyburg, Heilbronn, DE;
Gregor Meyers, Walddorfhaeslach, DE;
Andreas Ege, Teubingen, DE;
Christiane Fetzer, Meunster, DE;
Martina von Freyburg, Heilbronn, DE;
Boehringer Ingelheim Vetmedica GmbH, Ingelheim, DE;
Abstract
Attenuated pestiviruses, in particular attenuated BVDV, wherein at least one mutation is in the coding sequence for glycoprotein Eand at least another mutation in the coding sequence for Nwhich preferably leads to combined inactivation of the RNase activity residing in glycoprotein Ein addition to the inactivation of the (hypothesized) immunomodulating activity residing in N. Methods for attenuating pestiviruses such as BVDV, nucleic acids encoding the pestiviruses, in particular BVDV, compositions and vaccines comprising the attenuated pestiviruses, in particular BVDV, of the invention.