The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 11, 2009

Filed:

Dec. 16, 2005
Applicants:

Ian Foltz, Burnaby, CA;

Chadwick King, North Vancouver, CA;

Peter Koon Bong Ling, Vancouver, CA;

Jaspal Singh Kang, Surrey, CA;

Kathy Manchulenko, Port Coquitlam, CA;

Francine Chen, San Francisco, CA (US);

Caroline Darne Scatena, Alameda, CA (US);

Bruce A. Keyt, Hillsborough, CA (US);

Edwin Madison, San Francisco, CA (US);

Wayne R. Godfrey, Bainbridge Island, WA (US);

Stanislaw K. Morkowski, Lake Forest Park, WA (US);

Jennifer H. Richardson, Fremont, CA (US);

Inventors:

Ian Foltz, Burnaby, CA;

Chadwick King, North Vancouver, CA;

Peter Koon Bong Ling, Vancouver, CA;

Jaspal Singh Kang, Surrey, CA;

Kathy Manchulenko, Port Coquitlam, CA;

Francine Chen, San Francisco, CA (US);

Caroline Darne Scatena, Alameda, CA (US);

Bruce A. Keyt, Hillsborough, CA (US);

Edwin Madison, San Francisco, CA (US);

Wayne R. Godfrey, Bainbridge Island, WA (US);

Stanislaw K. Morkowski, Lake Forest Park, WA (US);

Jennifer H. Richardson, Fremont, CA (US);

Assignees:

Amgen Fremont Inc., Fremont, CA (US);

Dendreon Corporation, Seattle, WA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 51/00 (2006.01); C07H 21/04 (2006.01); C12N 5/06 (2006.01); C12P 21/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

Binding proteins, such as fully human monoclonal antibodies and fragments thereof, directed to the antigen Matriptase and uses of such binding proteins are disclosed. Nucleotide sequences encoding, and amino acid sequences comprising heavy and light chain immunoglobulin molecules capable of binding to Matriptase are also disclosed. The invention also discloses cell lines expressing such immunoglobulin molecules and monoclonal antibodies to Matriptase. The antibodies can be used to detect, prevent, and treat diseases such as cancer.


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