The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 11, 2009

Filed:

Mar. 26, 2003
Applicants:

John F. Kokai-kun, Frederick, MD (US);

Julie M. Adams, Columbia, MD (US);

James J. Mond, Silver Spring, MD (US);

Scott M. Walsh, Germantown, MD (US);

Anjali G. Shah, North Potomac, MD (US);

Tanya I. Chanturiya, Gaithersburg, MD (US);

Inventors:

John F. Kokai-Kun, Frederick, MD (US);

Julie M. Adams, Columbia, MD (US);

James J. Mond, Silver Spring, MD (US);

Scott M. Walsh, Germantown, MD (US);

Anjali G. Shah, North Potomac, MD (US);

Tanya I. Chanturiya, Gaithersburg, MD (US);

Assignee:

Biosynexus Incorporated, Gaithersburg, MD (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/46 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods for treating patients in which damaged tissue or an indwelling prosthetic device or catheter has a bacterial biofilm growing thereon, to at least partially disrupt said biofilm, by administering at least one antibacterial enzyme that is lethal or damaging to the biofilm-forming bacteria in an amount that is effective to at least partially disrupt the biofilm upon contact therewith. Methods for prophylactically treating a patient, and methods for disinfecting or sterilizing a surface ex-vivo to remove a biofilm or prevent biofilm growth are also disclosed, as well as implantable articles susceptible to biofilm growth to which a prophylactic coating of an antibacterial enzyme has been applied.


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