The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 04, 2009
Filed:
Jul. 31, 2007
Ali Khamene, Princeton, NJ (US);
Charles Henri Florin, Exton, PA (US);
Juan Carlos Celi, Bensheim, DE;
Barbara Ofstad, Weinheim, DE;
Mikael Rousson, Trenton, NJ (US);
Frank Sauer, Princeton, NJ (US);
Christian Schaller, Teublitz, DE;
Ali Khamene, Princeton, NJ (US);
Charles Henri Florin, Exton, PA (US);
Juan Carlos Celi, Bensheim, DE;
Barbara Ofstad, Weinheim, DE;
Mikael Rousson, Trenton, NJ (US);
Frank Sauer, Princeton, NJ (US);
Christian Schaller, Teublitz, DE;
Siemens Medical Solutions USA, Inc., Malvern, PA (US);
Siemens Aktiengesellschaft, München, DE;
Abstract
A method for four-dimensional (4D) image verification in respiratory gated radiation therapy, includes: acquiring 4D computed tomography (CT) images, each of the 4D CT images representing a breathing phase of a patient and tagged with a corresponding time point of a first surrogate signal; acquiring fluoroscopic images of the patient under free breathing, each of the fluoroscopic images tagged with a corresponding time point of a second surrogate signal; generating digitally reconstructed radiographs (DRRs) for each breathing phase represented by the 4D CT images; generating a similarity matrix to assess a degree of resemblance in a region of interest between the DRRs and the fluoroscopic images; computing a compounded similarity matrix by averaging values of the similarity matrix across different time points of the breathing phase during a breathing period of the patient; determining an optimal time point synchronization between the DRRs and the fluoroscopic images by using the compounded similarity matrix; and acquiring a third surrogate signal and turning a treatment beam on or off according to the optimal time point synchronization.