The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2009

Filed:

Mar. 07, 1997
Applicants:

Leif Christensen, Charlottenlund, DK;

Henrik Frydenlund Hansen, Radovre, DK;

Peter E. Nielsen, 2980 Kokkedal, DK;

Inventors:

Leif Christensen, Charlottenlund, DK;

Henrik Frydenlund Hansen, Radovre, DK;

Peter E. Nielsen, 2980 Kokkedal, DK;

Assignee:

Other;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C07K 7/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention concerns compositions comprising a nucleic acid mimic. The compositions may be used in the diagnosis and treatment of diseases amenable through modulation of nucleic acids which encode proteins that are implicated in disease states. In accordance with preferred embodiments, mimics are comprised of non-naturally occurring backbones to which are appended modified heterocyclic bases. Such bases preferably have sterically bulky substituents 1, 2, or 3 atoms removed from the sites of attachment to the backbone.


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