The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2009

Filed:

Dec. 13, 2002
Applicants:

Nicholas D. P. Cosford, San Diego, CA (US);

Chixu Chen, San Diego, CA (US);

Brian W. Eastman, San Diego, CA (US);

Dehua Huang, San Diego, CA (US);

Benito Munoz, San Diego, CA (US);

Petpiboon Prasit, San Diego, CA (US);

Nicholas D. Smith, San Diego, CA (US);

Inventors:

Nicholas D. P. Cosford, San Diego, CA (US);

Chixu Chen, San Diego, CA (US);

Brian W. Eastman, San Diego, CA (US);

Dehua Huang, San Diego, CA (US);

Benito Munoz, San Diego, CA (US);

Petpiboon Prasit, San Diego, CA (US);

Nicholas D. Smith, San Diego, CA (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4439 (2006.01); A61K 31/4155 (2006.01); C07D 401/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Pyrazole compounds substituted directly, or by a bridge, with a heteroaryl moiety containing N adjacent to the point of connection of the heteroaryl, are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, bipolar disorder and panic, as well as in the treatment of pain, circadian rhythm disorders, and other diseases.


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