The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 04, 2009
Filed:
Sep. 13, 2004
Applicants:
Laurent Francois Andre Hennequin, Reims, FR;
Christopher Thomas Halsall, Macclesfield, GB;
Inventors:
Laurent Francois Andre Hennequin, Reims, FR;
Christopher Thomas Halsall, Macclesfield, GB;
Assignee:
Astrazeneca AB, Sodertalje, SE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01); C07D 239/94 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention concerns quinazoline derivatives of the Formula (I); wherein each of R, R, W, X, X, Z, a and b are as defined in the description; processes for their preparation; pharmaceutical compositions containing them and their use in the manufacture of a medicament for providing an anti-proliferative effect. The quinazoline derivatives of Formula (I) are expected to be useful in the treatment of diseases such as certain cancers mediated by erbB receptor tyrosine kinases, particularly EGFR tyrosine kinase.