The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2009

Filed:

May. 27, 2004
Applicants:

Yong-hoon Chung, Seoul, KR;

Hak-sup Lee, Gangwon-do, KR;

Ki-wan Yi, Gyeonggi-do, KR;

Youn-hwa Heo, Seoul, KR;

Jae-youn Kim, Seoul, KR;

Inventors:

Yong-Hoon Chung, Seoul, KR;

Hak-sup Lee, Gangwon-do, KR;

Ki-Wan Yi, Gyeonggi-do, KR;

Youn-Hwa Heo, Seoul, KR;

Jae-Youn Kim, Seoul, KR;

Assignee:

Medexgen Co., Ltd., Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/00 (2006.01); C07K 14/475 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed is a protein variant which substitutes valine for phenylalanine residue in a binding domain having a biological response-modifying function by binding to a receptor, ligand or substrate. Also, the present invention discloses a DNA encoding the protein variant, a recombinant expression vector to which the DNA is operably linked, a host cell transformed or transfected with the recombinant expression vector, and a method of preparing the protein variant comprising cultivating the host cell and isolating the protein variant from the resulting culture. Further, the present invention discloses a pharmaceutical composition comprising the protein variant and a pharmaceutically acceptable carrier.


Find Patent Forward Citations

Loading…