The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7569352 B1

PDF
Full Text
Expired
Date of Patent:
Aug. 04, 2009

Filed:

May. 13, 2004
Applicants:

Petra Von Stein, Spanga, SE;

Patrik Andersson, Molndal, SE;

Nikolai Kouznetsov, Jarfalla, RU;

Lorenz Poellinger, Stockholm, SE;

Inventors:

Petra Von Stein, Spanga, SE;

Patrik Andersson, Molndal, SE;

Nikolai Kouznetsov, Jarfalla, RU;

Lorenz Poellinger, Stockholm, SE;

Assignee:

InDex Pharmaceuticals AB, Stockholm, SE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/52 (2006.01); G01N 33/567 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Agents useful for modulating the dioxin/aryl hydrocarbon receptor (AhR) can now be identified by determining the binding to said receptor and whether said agent suppresses or inhibits the expression of a gene substantially consisting of a sequence according to one of SEQ. ID. NO. 1 and SEQ. ID. NO. 2; a nucleotide sequence functionally homologous, or substantially homologous, or at least 90% identical to one of SEQ. ID. NO. 1 and SEQ. ID. NO. 2; and a nucleotide sequence complementary to the nucleotide sequence of SEQ. ID. NO. 1 or SEQ. ID. NO. 2. Such agents find utility in pharmaceutical compositions and methods for the prevention, alleviation or treatment of diseases involving gastrointestinal hyperplasia, such as gastrointestinal cancer or gastric cancer.


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