The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2009

Filed:

Aug. 12, 2005
Applicants:

Kathleen M. Schmainda, Elm Grove, WI (US);

Christopher Quarles, Milwaukee, WI (US);

B. Douglas Ward, West Allis, WI (US);

Inventors:

Kathleen M. Schmainda, Elm Grove, WI (US);

Christopher Quarles, Milwaukee, WI (US);

B. Douglas Ward, West Allis, WI (US);

Assignee:

The MCW Research Foundation, Milwaukee, WI (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/05 (2006.01);
U.S. Cl.
CPC ...
Abstract

One or two sets of time course NMR data are acquired using an EPI pulse sequence in which either or both gradient recalled echo NMR signals and spin-echo NMR signals are acquired after bolus injection of a contrast agent. T* relaxation rates for GE and Trelaxation rates for SE are calculated from the acquired NMR signals and are corrected for extravasation of contrast agent into surrounding tissues. The gradient-echo signals and spin-echo NMR signals are employed along with the T* and Trelaxation rates to calculate hemodynamic parameter maps which are used as a measure of tumor angiogenesis.


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