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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7566568 B1

PDFFull Text
Expired
Date of Patent:
Jul. 28, 2009

Filed:

Apr. 27, 2001

Method for generating highly active human dendritic cells from peripheral blood mononuclear cells

Applicants:

Filippo Belardelli, Rome, IT;

Stefano Maria Santini, Rome, IT;

Stefania Parlato, Rome, IT;

Tiziana Di Pucchio, Isola del Liri, IT;

Mariantonia Logozzi, Rome, IT;

Caterina Lapenta, Florence, IT;

Maria Ferrantini, Rome, IT;

Laura Santodonato, Rome, IT;

Giuseppina D'agostino, Rome, IT;

Inventors:

Filippo Belardelli, Rome, IT;

Stefano Maria Santini, Rome, IT;

Stefania Parlato, Rome, IT;

Tiziana Di Pucchio, Isola del Liri, IT;

Mariantonia Logozzi, Rome, IT;

Caterina Lapenta, Florence, IT;

Maria Ferrantini, Rome, IT;

Laura Santodonato, Rome, IT;

Giuseppina D'Agostino, Rome, IT;

Assignee:

Istituto Superiore di Sanita, Rome, IT;

Attorney:

Young & Thompson

Primary Examiner:

G R Ewoldt

Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a process for deriving dendritic cells from mononuclear cells in culture comprising the step of putting in contact type I IFN with said mononuclear cells. Dendritic cells suitable as cellular adjuvants in prophylactic as well as therapeutic vaccination of animal and human beings, are obtainable thereby, after a single step treatment in a brief period of time. Dendritic cells obtainable thereby, pharmaceutical compositions including them, in particular a vaccine comprising said cells as active principle, and a method of treatment of a pathology associated with the presence of an antigen in human beings, are further objects of the invention, as well as a kit for deriving said dendritic cells and a method for the ex vivo expansion of T cells using them.

Find Patent Forward Citations

Belardelli, Filippo. (2009). Method for generating highly active human dendritic cells from peripheral blood mononuclear cells (U.S. Patent No. 7566568). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7566568

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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