The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 21, 2009
Filed:
May. 18, 2005
J. Bruce Pitner, Durham, NC (US);
Douglas B. Sherman, Durham, NC (US);
Arounaguiry Ambroise, Morrisville, NC (US);
Joseph Thomas, Raleigh, NC (US);
J. Bruce Pitner, Durham, NC (US);
Douglas B. Sherman, Durham, NC (US);
Arounaguiry Ambroise, Morrisville, NC (US);
Joseph Thomas, Raleigh, NC (US);
Becton, Dickinson & Company, Franklin Lakes, NJ (US);
Abstract
Reactive fluorescent dyes compositions and methods of using same are disclosed. Squaraine nucleus, Nile Red nucleus, benzodioxazole nucleus, coumarin nucleus or aza coumarin nucleus dyes are disclosed having thiol-reactive groups. Squaraine nucleus, Nile Red nucleus, benzodioxazole nucleus, coumarin nucleus or aza coumarin nucleus dyes are disclosed that exhibit a fluorescence emission of at least about 575 nm. Biosensors are disclosed having a binding protein and a squaraine nucleus, Nile Red nucleus, benzodioxazole nucleus, coumarin nucleus or aza coumarin nucleus.