The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 21, 2009
Filed:
Nov. 07, 2006
Joachim-heiner Jendralla, Frankfurt, DE;
Guenter Billen, Niedernhausen, DE;
Wendelin Frick, Hunstetten-Beuerbach, DE;
Bernd Junker, Bad Soden, DE;
Theodor Andreas Wollman, Hattersheim, DE;
Joachim-Heiner Jendralla, Frankfurt, DE;
Guenter Billen, Niedernhausen, DE;
Wendelin Frick, Hunstetten-Beuerbach, DE;
Bernd Junker, Bad Soden, DE;
Theodor Andreas Wollman, Hattersheim, DE;
Sanofi-Aventis Deutschland GmbH, Frankfurt am Main, DE;
Abstract
The present invention is a process for the preparation of diphenylazetidinone derivatives of the formula (I) or forms thereof comprising the substituents X, Rand/or Ras defined herein. More specifically, the invention comprises methods for the preparation of these compounds by cyclization of certain β-amino carboxamides or β-amino carboxylic esters. These diphenylazetidinone compounds are useful in the treatment of high blood serum cholesterol levels and the maintenance of the reduced cholesterol levels achieved thereby.