The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 21, 2009
Filed:
Jan. 22, 2004
Tasuku Honjo, Kyoto-shi, Kyoto, JP;
Shiro Shibayama, Mishima-gun, JP;
Kazuhiko Takeda, Mishima-gun, JP;
Masayoshi Matsuo, Mishima-gun, JP;
Takao Yoshida, Mishima-gun, JP;
Masakazu Miyamoto, Mishima-gun, JP;
Tasuku Honjo, Kyoto-shi, Kyoto, JP;
Shiro Shibayama, Mishima-gun, JP;
Kazuhiko Takeda, Mishima-gun, JP;
Masayoshi Matsuo, Mishima-gun, JP;
Takao Yoshida, Mishima-gun, JP;
Masakazu Miyamoto, Mishima-gun, JP;
Ono Pharmaceutical Co., Ltd., Osaka, JP;
Other;
Abstract
The present invention relates to a substance specific to human PD-1 comprising a part that recognizes human PD-1, a part that recognizes a membrane protein in cell membrane of human PD-1-expressing cells, and linkers. Since the substance specific to human PD-1 selectively can recognize human PD-1 and a membrane protein on cell membrane of human PD-1-expressing cells and can transmit inhibitory signal of human PD-1, it is useful for therapy and/or prevention of diseases caused by immunopathy.