The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 21, 2009

Filed:

Jan. 17, 2003
Applicants:

Chaim M. Roifman, North York, CA;

Peter Demin, Moscow, RU;

Thomas Grunberger, Toronto, CA;

Olga Rounova, Moscow, RU;

Octavian Laurand Cimpean, Thornhill, CA;

Inventors:

Chaim M. Roifman, North York, CA;

Peter Demin, Moscow, RU;

Thomas Grunberger, Toronto, CA;

Olga Rounova, Moscow, RU;

Octavian Laurand Cimpean, Thornhill, CA;

Assignee:

The Hospital for Sick Children, Toronto, Ontario, CA;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 255/03 (2006.01); A61K 31/275 (2006.01);
U.S. Cl.
CPC ...
Abstract

The following compounds of formulae (I) and (III) which may be useful in treating a variety of cell proliferative disorders are disclosed: Formula (I), (II), wherein R, Rand Rare each independently selected from H, OH, Calkyl, Calkoxy, NH, NH—Calkyl, N(Calkyl), SH, S—Calkyl, NO, CF, OCFand halo; Ris unsubstituted Ar, or Ar substituted with 1-4 substituents, independently selected from Calkyl, Calkoxy and halo; X is selected from (CHCHO)and (CH), and n=1-4.


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