The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7563612 B1

Expired

Date of Patent:

Jul. 21, 2009

Filed:

Sep. 26, 2005

Recombinant bifunctional protein of human lutropin receptor and human chorionic gonadotropin b-subunit and uses thereof

Applicants:

Brij B. Saxena, Englewood, NJ (US);

Premila Rathnam, Englewood Cliffs, NJ (US);

Makul Singh, Teaneck, NJ (US);

Meirong Hao, Rego Park, NY (US);

Inventors:

Brij B. Saxena, Englewood, NJ (US);

Premila Rathnam, Englewood Cliffs, NJ (US);

Makul Singh, Teaneck, NJ (US);

Meirong Hao, Rego Park, NY (US);

Assignee:

Cornell Research Foundation, Inc., Ithaca, NY (US);

Attorney:

Nixon Peabody LLP

Primary Examiner:

Bridget E Bunner

Assistant Examiner:

Christina Borgeest

Int. Cl.

CPC ...

C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/16 (2006.01); C12N 15/62 (2006.01); C12N 15/63 (2006.01); A61K 38/24 (2006.01);

U.S. Cl.

CPC ...

Abstract

The present invention relates to a chimeric nucleic acid molecule encoding a fusion protein having a human lutropin hormone-receptor domain and a human chorionic gonadotropin-β subunit domain, the isolated human lutropin hormone-receptor/human chorionic gonadotropin-β fusion protein, and antibodies which recognize part or all the domains of the fusion protein. Also provided are compositions having the human lutropin hormone-receptor/human chorionic gonadotropin-β fusion protein and a pharmaceutical carrier and compositions including antibodies to the fusion protein and a pharmaceutical carrier. The present invention also relates to methods of treating androgen-excess-mediated disease conditions by administering to a subject an antibody to the human lutropin hormone-receptor/human chorionic gonadotropin-β fusion protein under conditions suitable to treat the conditions, and methods of immunocontraception that involve administering to a subject the chimeric nucleic acid molecule encoding the human lutropin hormone receptor/human chorionic gonadotropin-β fusion protein, the fusion protein in whole or in part, or antibodies thereto.

Find Patent Forward Citations

Saxena, Brij. (2009). Recombinant bifunctional protein of human lutropin receptor and human chorionic gonadotropin b-subunit and uses thereof (U.S. Patent No. 7563612). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7563612

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