The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2009
Filed:
Jan. 19, 2007
Applicants:
Jing-ping Liou, Taipei, TW;
Jang-yang Chang, Taipei, TW;
Inventors:
Jing-Ping Liou, Taipei, TW;
Jang-Yang Chang, Taipei, TW;
Assignees:
Taipei Medical University, , TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/075 (2006.01); A61K 31/136 (2006.01); C07C 211/45 (2006.01); C07C 43/205 (2006.01);
U.S. Cl.
CPC ...
Abstract
A series of Z-stilbenes derivatives are disclosed, which have the structure as shown by formula 1. In the structure of formula 1, X is hydrogen, NHR, or nitro group, and R is hydrogen. Y and Z is independently hydrogen, halogen, C-Calkyl, or C-Calkoxyl. Furthermore, A is hydrogen, hydroxyl, or amino group. The compounds of the present invention have both aqueous solubility and anti-tumor activity. The Z-stilbenes derivatives of the present invention can further include a pharmaceutical carrier to form pharmaceutical compositions as potent anti-mitotic agents and anti-cancer agents.