The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2009

Filed:

Jan. 21, 2002
Applicants:

Hai Wang, Beijing, CN;

Liuhong Yun, Beijing, CN;

Huasong Feng, Beijing, CN;

Fulin LI, Beijing, CN;

Xingchun Tang, Beijing, CN;

Huamei He, Beijing, CN;

Rifang Yang, Beijing, CN;

Wenyu Cui, Beijing, CN;

Qixiu Gao, Beijing, CN;

Gang HU, Beijing, CN;

Rusheng Zhao, Beijing, CN;

Wei Liu, Beijing, CN;

Chaoliang Long, Beijing, CN;

Lin Wang, Beijing, CN;

Xinqiang LU, Beijing, CN;

Lijun Liu, Beijing, CN;

Yuan Yan, Beijing, CN;

Inventors:

Hai Wang, Beijing, CN;

Liuhong Yun, Beijing, CN;

Huasong Feng, Beijing, CN;

Fulin Li, Beijing, CN;

Xingchun Tang, Beijing, CN;

Huamei He, Beijing, CN;

Rifang Yang, Beijing, CN;

Wenyu Cui, Beijing, CN;

Qixiu Gao, Beijing, CN;

Gang Hu, Beijing, CN;

Rusheng Zhao, Beijing, CN;

Wei Liu, Beijing, CN;

Chaoliang Long, Beijing, CN;

Lin Wang, Beijing, CN;

Xinqiang Lu, Beijing, CN;

Lijun Liu, Beijing, CN;

Yuan Yan, Beijing, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); A61K 31/405 (2006.01); C07C 211/00 (2006.01); C07D 211/70 (2006.01); C07D 209/18 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides amine derivatives represented by formula I, its isomers, racemes or optical isomers, pharmaceutical salts thereof, its amides or esters, pharmaceutical compositions containing said compounds and the preparation methods thereof. The invention also relates to the use of the above mentioned compounds in the preparation of drugs for the prophylaxis or treatment of cardiovascular diseases, diabetes, bronchial and urinary smooth muscle spasm as well as ischemic and anoxic nerve injury. The above compounds can be used to treat hypertension, angina diaphragmatic, myocardial infarction, congestive heart failure, arrhythmia, diabetes, spasmodic bronchial diseases, spasmodic bladder or ureter diseases, and depression.


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