The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2009

Filed:

Nov. 10, 2004
Applicants:

Erkki Ruoslahti, Rancho Santa Fe, CA (US);

Darren M. Brown, Carlsbad, CA (US);

Inventors:

Erkki Ruoslahti, Rancho Santa Fe, CA (US);

Darren M. Brown, Carlsbad, CA (US);

Assignee:

The Burnham Institute, La Jolla, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); G01N 33/53 (2006.01); G01N 33/566 (2006.01); G01N 33/48 (2006.01); G01N 33/00 (2006.01); C12Q 1/70 (2006.01); C07K 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Metadherin, a protein that controls metastasis, and variants of metadherin are described. DNA sequences encoding the same and methods of production are described. Therapies involving the application of metadherin, binding agents that bind to metadherin, such as antibodies, and expression modulating agents, such as siRNA, are described. The use of metadherin or metadherin variants for delivering desired substances to particular lung tissue is described. A method of diagnosing metastatic cells based on the presence of metadherin is described.


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