The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2009
Filed:
Sep. 09, 2005
Irit Pinchasi, Ra'anana, IL;
Ben-zion Dolitzky, Petach-Tikva, IL;
Anton Frenkel, Modiin, IL;
Michal Schwartz, Rehovot, IL;
Ruth Arnon, Rehovot, IL;
Rina Aharoni, Rehovot, IL;
Irit Pinchasi, Ra'anana, IL;
Ben-Zion Dolitzky, Petach-Tikva, IL;
Anton Frenkel, Modiin, IL;
Michal Schwartz, Rehovot, IL;
Ruth Arnon, Rehovot, IL;
Rina Aharoni, Rehovot, IL;
Yeda Research and Development Co., Ltd., Rehovot, IL;
Abstract
The invention provides a composition comprising a mixture of polypeptides, wherein each polypeptide (a) is a copolymer of the amino acids L-glutamic acid, L-alanine, L-tyrosine, and L-lysine, and (b) may be in the form of a pharmaceutically acceptable salt; and wherein in the mixture (i) the polypeptides have an average molecular weight in the range 13,500 to 18,500 daltons, (ii) 13% to 38% of the polypeptides have a diethylamide group instead of a carboxyl group present at one end thereof, and (iii) 68% of the polypeptides have a molecular weight between 7,000 and 41,000 daltons. In an embodiment, the average molecular weight is 16,000 daltons. The invention also provides a method of treating a human subject afflicted with a neurodegenerative disease comprising administering to the human subject a therapeutically effective amount of any of the disclosed compositions so as to thereby treat the human subject.