The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2009
Filed:
Aug. 06, 2008
Shaoqing Chen, Bridgewater, NJ (US);
Nicholas J. S. Huby, Scotch Plains, NJ (US);
Norman Kong, West Caldwell, NJ (US);
John Anthony Moliterni, Bloomfield, NJ (US);
Omar Jose Morales, New Milford, NJ (US);
Shaoqing Chen, Bridgewater, NJ (US);
Nicholas J. S. Huby, Scotch Plains, NJ (US);
Norman Kong, West Caldwell, NJ (US);
John Anthony Moliterni, Bloomfield, NJ (US);
Omar Jose Morales, New Milford, NJ (US);
Hoffman-La Roche Inc., Nutley, NJ (US);
Abstract
This invention relates to compounds of formula I: or pharmaceutically acceptable salts thereof,wherein R1, R2, R3, R4, R5, and R6 are described in this application. These compounds inhibit the enzymes MEK 1 and MEK2, protein kinases that are components of the MAP kinase signal transduction pathway and as such the compounds will have anti-hyperproliferative cellular activity.