The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2009
Filed:
Jul. 28, 2006
Kevin Brown, Philadelphia, PA (US);
Timothy J. Doyle, Morristown, NJ (US);
John W. F. Whitehead, Newtown, PA (US);
Kevin Brown, Philadelphia, PA (US);
Timothy J. Doyle, Morristown, NJ (US);
John W. F. Whitehead, Newtown, PA (US);
Purdue Pharma L.P., Stamford, CT (US);
Abstract
Methods, composition, and intermediates are disclosed that are useful for making 4-Tetrazolyl-4-phenylpiperidine Compounds according to Formula I, where Aris —C-Ccycloalkyl, phenyl, naphthyl, anthryl, phenanthryl or -(5-7-membered) heteroaryl, each being unsubstituted or substituted with one or more Rgroups; Aris phenyl, naphthyl, anthryl, phenanthryl or -(5-7-membered) heteroaryl, each being unsubstituted or substituted with one or more Rgroups; Zand Zare each independently a —(C-Calkyl) group; Ris —(CH)C(O)N(R)(R) where Rand Rare each independently H or —(C-Calkyl); Ris halogen, —C-Calkyl, —O—(C-Calkyl), —NH(C-Calkyl) or —N(C-Calkyl); n is an integer ranging from 1 to 4; m is an integer ranging from 0 to 4; and, in certain embodiments, the phenyl moiety attached to the 4-position of the piperidine ring of a compound according to Formula I can be optionally substituted with one or more Rgroups.