The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2009
Filed:
Mar. 30, 2005
Dominique Lombardo, Marseille, FR;
Eric Mas, Marseille, FR;
Marie-odile Sadoulet, Marseille, FR;
Laurence Panicot-dubois, Canohes, FR;
Jean-paul Bernard, Marseille, FR;
Dominique Lombardo, Marseille, FR;
Eric Mas, Marseille, FR;
Marie-Odile Sadoulet, Marseille, FR;
Laurence Panicot-Dubois, Canohes, FR;
Jean-Paul Bernard, Marseille, FR;
Universite de la Mediterranee, Marseilles, FR;
Institut National de la Sante et de la Recherche Medicale, Paris, FR;
Abstract
The invention relates to a glycopeptide comprising between 1 and 40 repeated C-terminal polypeptides, with 11 amino acids, of BSDL or FAPP, whereby the aforementioned polypeptides are glycosylated and bear glycosylated epitopes giving rise to a specific immunological reaction with induced antibodies in a patient suffering from type 1 diabetes, and/or purified from biological fluids of human or animal origin or recombinant and produced by expression in a standard host cell comprising an enzymatic material necessary for priming a glycosylation, said host cell being genetically modified such as to comprise a gene coding for the aforementioned polypeptides and a gene coding for one or more enzymes selected from among glycosyltransferases and anti-glycopeptide antibodies. The invention also relates to the applications thereof in therapeutics and diagnostics.