The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2009
Filed:
Mar. 19, 2004
Richard Dennis Dimarchi, Carmel, IN (US);
Wolfgang Glaesner, Indianapolis, IN (US);
Rohn Lee Millican, Jr., Indianapolis, IN (US);
Andrew Mark Vick, Fishers, IN (US);
Lianshan Zhang, Carmel, IN (US);
Richard Dennis DiMarchi, Carmel, IN (US);
Wolfgang Glaesner, Indianapolis, IN (US);
Rohn Lee Millican, Jr., Indianapolis, IN (US);
Andrew Mark Vick, Fishers, IN (US);
Lianshan Zhang, Carmel, IN (US);
Eli Lilly and Company, Indianapolis, IN (US);
Abstract
The invention provides GLP-1 compounds coupled to at least one polyethylene glycol molecule or derivative thereof, resulting in a biologically active peptide with an extended half-life and a slower clearance when compared to that of unPEGylated peptide. These PEGylated GLP-1 compounds and compositions are useful in treating diabetes, obesity, irritable bowel syndrome and other conditions that would be benefited by lowering plasma glucose, inhibiting gastric and/or intestinal motility and inhibiting gastric and/or intestinal emptying, or inhibiting food intake.