The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2009
Filed:
Jul. 25, 2002
Pavandeep Aujla, Hayes, GB;
Timothy John Norman, Great Missenden, GB;
John Robert Porter, Chinnor, GB;
Stuart Bailey, Dorking, GB;
Stephen Brand, Reading, GB;
Pavandeep Aujla, Hayes, GB;
Timothy John Norman, Great Missenden, GB;
John Robert Porter, Chinnor, GB;
Stuart Bailey, Dorking, GB;
Stephen Brand, Reading, GB;
UCB Pharma, S.A., , BE;
Abstract
Compounds of formula (1) are described: in which X is an —O— or —S— atom or —N(R)— group and Ris a group ArLArAlk- in which Aris an optionally substituted aromatic or heteroaromatic group, Lis a covalent bond or a linker atom or group, Aris an optionally substituted bicyclic heteroarylene group and Alk is a chain —CH—CH(R)—, —CH═C(R)—, OR—CH(CHR)— in which R is a carboxylic acid (—COH) or a derivative or biostere thereof. The compounds are selective inhibitors of alpha 4 integrins such as αβand are of use in modulating cell adhesion for the prophylaxis or treatment of inflammatory diseases or disorders, such as rheumatoid arthritis, in which the extravasculation of leukocytes plays a role.