The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2009

Filed:

Nov. 22, 2006
Applicants:

Masaya Hashimoto, Tsukuba, JP;

Osamu Okamoto, Tsukuba, JP;

Satoshi Ozaki, Tsukuba, JP;

Hisashi Ohta, Tsukuba, JP;

Inventors:

Masaya Hashimoto, Tsukuba, JP;

Osamu Okamoto, Tsukuba, JP;

Satoshi Ozaki, Tsukuba, JP;

Hisashi Ohta, Tsukuba, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/438 (2006.01); C07D 401/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to 4-oxoimidazolidine-2-spiropiperidine derivatives represented by a general formula [I] [in which A, A, A, Aand Astand for optionally halogen-substituted methine, or nitrogen atom; Rand Rstand for lower alkyl or the like; Rstands for hydrogen or lower alkyl; Rand Rstand for hydrogen, or lower alkyl which is optionally substituted with hydroxy, or the like] or salts thereof. These compounds act as nociceptin receptor agonist, and are useful as analgesic, reliever from tolerance to narcotic analgesic, reliever from dependence on narcotic analgesic, analgesic enhancer, antiobestic, drug for ameliorating brain function, remedy for schizophrenia, drug for treating regressive neurodegenerative diseases, antianxiety agent or antidepressant and remedy for diabetes insipidus and polyuria; and the like.


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